2022 Big 12 Conference Leaders Interceptions - Games vs. Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cobee Bryant | Kansas | SO | CB | 8 | 3 | 86 | 1 | 0.38 |
| 1 | Malachi Ruffin | WVU | JR | DB | 9 | 2 | 43 | 1 | 0.22 |
| 1 | Cincere Mason | Kansas St | SR | S | 8 | 1 | 37 | 1 | 0.13 |
| 1 | Millard Bradford | TCU | SR | S | 8 | 1 | 36 | 1 | 0.13 |
| 1 | AJ McCarty | Baylor | SO | CB | 9 | 1 | 18 | 1 | 0.11 |
| 1 | Josh Newton | TCU | JR | CB | 10 | 1 | 57 | 1 | 0.10 |