2022 Big 12 Conference Leaders Interceptions - Games in November Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Josh Newton | TCU | JR | CB | 4 | 1 | 57 | 1 | 0.25 |
| 2 | Jaylan Ford | Texas | JR | LB | 4 | 3 | 48 | 0 | 0.75 |
| 3 | Malachi Ruffin | WVU | JR | DB | 4 | 1 | 43 | 1 | 0.25 |
| 4 | Cincere Mason | Kansas St | SR | S | 3 | 1 | 37 | 1 | 0.33 |
| 4 | Rich Miller | Kansas | SR | LB | 4 | 1 | 37 | 0 | 0.25 |
| 6 | Millard Bradford | TCU | SR | S | 4 | 1 | 36 | 1 | 0.25 |
| 7 | Devin Lemear | Baylor | FR | S | 4 | 1 | 31 | 0 | 0.25 |
| 8 | Jason Taylor II | Okla St | SR | S | 4 | 3 | 28 | 0 | 0.75 |
| 9 | Jonah Laulu | Oklahoma | SR | DL | 4 | 1 | 26 | 0 | 0.25 |
| 10 | Tre'Vius Hodges-Tomlinson | TCU | SR | CB | 4 | 2 | 20 | 0 | 0.50 |
| 11 | Beau Freyler | Iowa State | SO | DB | 4 | 1 | 18 | 0 | 0.25 |
| 12 | Mello Dotson | Kansas | SO | CB | 4 | 1 | 13 | 0 | 0.25 |
| 13 | C.J. Coldon | Oklahoma | SR | DB | 4 | 2 | 12 | 0 | 0.50 |
| 13 | Kendal Daniels | Okla St | FR | S | 4 | 1 | 12 | 0 | 0.25 |
| 15 | Billy Bowman Jr. | Oklahoma | SO | DB | 4 | 2 | 11 | 0 | 0.50 |
| 16 | Dillon Doyle | Baylor | SR | LB | 4 | 1 | 9 | 0 | 0.25 |
| 17 | Kobe Savage | Kansas St | JR | S | 2 | 1 | 3 | 0 | 0.50 |
| 17 | Danny Stutsman | Oklahoma | SO | LB | 4 | 1 | 3 | 0 | 0.25 |
| 19 | Drake Cheatum | Kansas St | SR | S | 4 | 1 | 1 | 0 | 0.25 |