2022 Conference USA Leaders Sacks - Games in August/September Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Middle Tennessee | 5 | 19.0 | 152 | 3.80 |
| 2 | Florida Atlantic | 5 | 11.0 | 52 | 2.20 |
| 3 | Western Kentucky | 4 | 10.0 | 59 | 2.50 |
| 4 | Rice | 4 | 8.0 | 55 | 2.00 |
| 4 | North Texas | 5 | 8.0 | 50 | 1.60 |
| 6 | UTSA | 5 | 7.0 | 36 | 1.40 |
| 7 | Florida International | 3 | 6.0 | 36 | 2.00 |
| 7 | UTEP | 5 | 6.0 | 27 | 1.20 |
| 9 | Charlotte | 5 | 5.0 | 26 | 1.00 |
| 9 | Louisiana Tech | 4 | 5.0 | 22 | 1.25 |
| 9 | UAB | 3 | 5.0 | 12 | 1.67 |