2022 Conference USA Leaders Passes Defended - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Middle Tennessee | 5 | 9 | 23 | 32 | 6.40 |
| 2 | UAB | 5 | 6 | 25 | 31 | 6.20 |
| 3 | Western Kentucky | 6 | 10 | 21 | 31 | 5.17 |
| 4 | UTEP | 4 | 2 | 18 | 20 | 5.00 |
| 5 | Louisiana Tech | 4 | 3 | 14 | 17 | 4.25 |
| 5 | Florida International | 4 | 1 | 16 | 17 | 4.25 |
| 7 | UTSA | 5 | 4 | 15 | 19 | 3.80 |
| 8 | Rice | 5 | 4 | 13 | 17 | 3.40 |
| 9 | Florida Atlantic | 4 | 2 | 7 | 9 | 2.25 |
| 10 | North Texas | 5 | 1 | 7 | 8 | 1.60 |
| 11 | Charlotte | 4 | 3 | 3 | 6 | 1.50 |