2021 National Leaders Passes Defended - Games in October Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Daiyan Henley | Nevada | SR | LB | 5 | 4 | 1 | 5 | 1.00 |
| 2 | Coby Bryant | Cincinnati | SR | CB | 5 | 3 | 6 | 9 | 1.80 |
| 2 | Darrell Luter Jr. | USA | JR | CB | 5 | 3 | 4 | 7 | 1.40 |
| 2 | Khoury Bethley | Hawai'i | SR | DB | 4 | 3 | 2 | 5 | 1.25 |
| 2 | Evan Williams | Fresno St | JR | DB | 4 | 3 | 2 | 5 | 1.25 |
| 2 | Cam Allen | Purdue | JR | S | 4 | 3 | 1 | 4 | 1.00 |
| 2 | Dashaun Jerkins | Vanderbilt | SR | S | 5 | 3 | 0 | 3 | 0.60 |
| 8 | Trenton Thompson | SDSU | SR | S | 4 | 2 | 8 | 10 | 2.50 |
| 8 | Jalen Graham | Purdue | JR | LB | 4 | 2 | 3 | 5 | 1.25 |
| 8 | Daxton Hill | Michigan | JR | DB | 4 | 2 | 3 | 5 | 1.25 |
| 8 | Eric Garror | La-Lafytte | JR | CB | 4 | 2 | 3 | 5 | 1.25 |
| 8 | DJ James | Oregon | SO | CB | 4 | 2 | 3 | 5 | 1.25 |
| 8 | R'Tarriun Johnson | ODU | JR | S | 4 | 2 | 3 | 5 | 1.25 |
| 8 | Malik Moore | BYU | JR | DB | 5 | 2 | 3 | 5 | 1.00 |
| 8 | Jordan Anderson | BGSU | JR | S | 5 | 2 | 3 | 5 | 1.00 |
| 8 | Quincy Riley | MTSU | FR | CB | 2 | 2 | 2 | 4 | 2.00 |
| 8 | Steven Jones Jr. | App St | SR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 8 | Gregory Grate | MTSU | JR | S | 4 | 2 | 2 | 4 | 1.00 |
| 8 | Tre Wortham | UConn | JR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 8 | Jordan Battle | Alabama | JR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 8 | Jason Taylor II | Okla St | JR | S | 4 | 2 | 2 | 4 | 1.00 |
| 8 | Nate Rutchena | California | FR | ILB | 4 | 2 | 2 | 4 | 1.00 |
| 8 | Elijah Hicks | California | SR | S | 4 | 2 | 2 | 4 | 1.00 |
| 8 | Deontai Williams | Nebraska | SR | S | 3 | 2 | 1 | 3 | 1.00 |
| 8 | Joey Blount | Virginia | SR | FS | 3 | 2 | 1 | 3 | 1.00 |
| 8 | Nakobe Dean | Georgia | JR | ILB | 4 | 2 | 1 | 3 | 0.75 |
| 8 | Steven Gilmore | Marshall | JR | DB | 4 | 2 | 1 | 3 | 0.75 |
| 8 | Cory McCoy | Marshall | SR | S | 4 | 2 | 1 | 3 | 0.75 |
| 8 | Tariq Drake | Ohio | SR | S | 4 | 2 | 1 | 3 | 0.75 |
| 8 | Charles Amankwaa | Akron | JR | DB | 4 | 2 | 1 | 3 | 0.75 |
| 8 | Cam'Ron Kelly | N Carolina | JR | DB | 4 | 2 | 1 | 3 | 0.75 |
| 8 | Cedric Gray | N Carolina | SO | LB | 4 | 2 | 1 | 3 | 0.75 |
| 8 | JT Woods | Baylor | SR | S | 4 | 2 | 1 | 3 | 0.75 |
| 8 | Naeem Smith | Rice | SR | S | 4 | 2 | 1 | 3 | 0.75 |
| 8 | Maxwell Worship | Vanderbilt | SR | S | 5 | 2 | 1 | 3 | 0.60 |
| 8 | Jaylen Watson | Wash St | SR | DB | 5 | 2 | 1 | 3 | 0.60 |
| 8 | Riley Moss | Iowa | SR | DB | 2 | 2 | 0 | 2 | 1.00 |
| 8 | Asa Turner | Washington | SO | DB | 3 | 2 | 0 | 2 | 0.67 |
| 8 | Shaq Bond | Utah State | SR | S | 4 | 2 | 0 | 2 | 0.50 |
| 8 | DQ Thomas | MTSU | SR | LB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Keith Sherald Jr. | Kent State | SR | CB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | John Petrishen | Pittsburgh | SR | LB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | B.J. Foster | Texas | SR | DB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Craig Young | Ohio State | SO | SAF | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Rashad Torrence II | Florida | SO | S | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Trey Franklin | Louisville | SO | DB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Dwayne Boyles | S Florida | SR | LB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Antonio Grier | S Florida | SR | LB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Kenneth Harris | Ark St | FR | CB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Jaylen McCollough | Tennessee | JR | DB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Jack Koerner | Iowa | SR | DB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Payton Wilgar | BYU | SO | LB | 5 | 2 | 0 | 2 | 0.40 |
| 8 | Deshawn Pace | Cincinnati | SO | LB | 5 | 2 | 0 | 2 | 0.40 |
| 8 | Keidron Smith | Miss | SR | DB | 5 | 2 | 0 | 2 | 0.40 |
| 55 | Cortez Davis | Hawai'i | SR | DB | 4 | 1 | 7 | 8 | 2.00 |
| 55 | Roger Cray | ODU | SR | CB | 3 | 1 | 6 | 7 | 2.33 |
| 55 | Zyon Gilbert | FAU | SR | CB | 4 | 1 | 6 | 7 | 1.75 |
| 55 | Erick Hallett II | Pittsburgh | JR | DB | 4 | 1 | 5 | 6 | 1.50 |
| 55 | Tyreek Chappell | Texas A&M | FR | DB | 4 | 1 | 5 | 6 | 1.50 |
| 55 | Malik Fleming | ECU | SO | CB | 4 | 1 | 5 | 6 | 1.50 |
| 55 | Cam Taylor-Britt | Nebraska | JR | CB | 4 | 1 | 5 | 6 | 1.50 |
| 55 | Nehemiah Shelton | SJSU | SR | CB | 5 | 1 | 5 | 6 | 1.20 |
| 55 | Josh Newton | La-Monroe | SO | CB | 5 | 1 | 5 | 6 | 1.20 |
| 55 | Davonte Brown | UCF | SO | DB | 5 | 1 | 5 | 6 | 1.20 |
| 55 | Damarion Williams | Houston | SR | CB | 4 | 1 | 4 | 5 | 1.25 |
| 55 | Travon Fuller | Tulsa | SR | CB | 4 | 1 | 4 | 5 | 1.25 |
| 55 | Tre Bugg III | Air Force | SR | DB | 4 | 1 | 4 | 5 | 1.25 |
| 55 | Trey Dean III | Florida | SR | S | 4 | 1 | 4 | 5 | 1.25 |
| 55 | Qwynnterrio Cole | Louisville | SR | DB | 4 | 1 | 4 | 5 | 1.25 |
| 55 | Ja'Quan McMillian | ECU | SO | CB | 4 | 1 | 4 | 5 | 1.25 |
| 55 | Will Ignont | Western Ky | JR | LB | 5 | 1 | 4 | 5 | 1.00 |
| 55 | Devin Taylor | BGSU | SR | CB | 5 | 1 | 4 | 5 | 1.00 |
| 55 | Duron Lowe | Liberty | SR | CB | 5 | 1 | 4 | 5 | 1.00 |
| 55 | Alex Hogan | Houston | JR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Marcus Jones | Houston | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Reddy Steward | Troy | SO | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Antavious Lane | Georgia St | SO | S | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Trey Cobb | App St | SR | ILB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Nazeeh Johnson | Marshall | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Jack Jones | Ariz St | SR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Shyheim Battle | NC State | FR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Aydan White | NC State | FR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Russ Yeast | Kansas St | SR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Lance Boykin | Coast Car | JR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | J.T. Wahee | Ball State | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Korel Smith | FAU | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Romain Mungin | FAU | SO | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Hugh Nelson II | Hawai'i | JR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | LJ Early | Fresno St | SR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Miles McCord | Rice | JR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Brandon Joseph | N'western | SO | SAF | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Bryce Watts | U Mass | JR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Dwight McGlothern | LSU | SO | CB | 4 | 1 | 3 | 4 | 1.00 |
| 55 | Jakob Robinson | BYU | FR | DB | 5 | 1 | 3 | 4 | 0.80 |
| 55 | Antwon Kincade | Western Ky | SR | DB | 5 | 1 | 3 | 4 | 0.80 |
| 55 | Caesar Williams | Wisconsin | SR | CB | 5 | 1 | 3 | 4 | 0.80 |
| 55 | Collin Wilder | Wisconsin | SR | S | 5 | 1 | 3 | 4 | 0.80 |
| 55 | JoJuan Claiborne | Nevada | SR | DB | 5 | 1 | 3 | 4 | 0.80 |
| 55 | Dadrion Taylor-Demerson | Texas Tech | JR | DB | 5 | 1 | 3 | 4 | 0.80 |
| 55 | Kadofi Wright | Buffalo | SR | LB | 5 | 1 | 3 | 4 | 0.80 |