2021 National Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Terrance Taylor | Toledo | JR | OLB | 1 | 2.0 | 17 | 2.00 |
| 2 | Collin Oliver | Okla St | FR | DE | 4 | 6.0 | 46 | 1.50 |
| 2 | Nick Herbig | Wisconsin | SO | OLB | 3 | 4.5 | 22 | 1.50 |
| 2 | Jacoby Windmon | UNLV | JR | ILB | 2 | 3.0 | 29 | 1.50 |
| 2 | Storey Jackson | Liberty | SR | LB | 2 | 3.0 | 16 | 1.50 |
| 2 | Nick Hampton | App St | JR | OLB | 2 | 3.0 | 10 | 1.50 |
| 2 | TJ Johnson | Marshall | SR | DL | 1 | 1.5 | 9 | 1.50 |
| 8 | Terrel Bernard | Baylor | SR | LB | 4 | 5.5 | 35 | 1.38 |
| 9 | Aidan Hutchinson | Michigan | SR | DE | 4 | 5.0 | 31 | 1.25 |
| 9 | Jeremy Lewis | ECU | SO | OLB | 2 | 2.5 | 20 | 1.25 |
| 9 | Cory Durden | NC State | SR | DT | 2 | 2.5 | 9 | 1.25 |
| 9 | Scott Patchan | CSU | SR | DL | 2 | 2.5 | 8 | 1.25 |
| 13 | Tomon Fox | N Carolina | SR | LB | 4 | 4.5 | 25 | 1.13 |
| 13 | Keir Thomas | FSU | SR | DE | 4 | 4.5 | 19 | 1.13 |
| 15 | Will McDonald IV | Iowa State | JR | DE | 5 | 5.0 | 32 | 1.00 |
| 15 | Will Anderson Jr. | Alabama | SO | LB | 5 | 5.0 | 31 | 1.00 |
| 15 | Byron Young | Tennessee | JR | DL | 4 | 4.0 | 35 | 1.00 |
| 15 | Brock Martin | Okla St | SR | DE | 3 | 3.0 | 16 | 1.00 |
| 15 | Nick Heninger | Utah State | SR | DE | 2 | 2.0 | 35 | 1.00 |
| 15 | Isaiah Foskey | Notre Dame | SO | DL | 2 | 2.0 | 21 | 1.00 |
| 15 | Zach VanValkenburg | Iowa | SR | DL | 2 | 2.0 | 16 | 1.00 |
| 15 | Darian Varner | Temple | FR | DT | 2 | 2.0 | 15 | 1.00 |
| 15 | Garret Fountain | SDSU | SO | LB | 2 | 2.0 | 14 | 1.00 |
| 15 | Joey Noble | New Mexico | SR | DE | 2 | 2.0 | 14 | 1.00 |
| 15 | Rick D'Abreu | ECU | SO | DL | 2 | 2.0 | 14 | 1.00 |
| 15 | Vince Sanford | Air Force | JR | OLB | 2 | 2.0 | 12 | 1.00 |
| 15 | Ty Shelby | La-Monroe | SR | DE | 2 | 2.0 | 11 | 1.00 |
| 15 | R.J. Oben | Duke | SO | DE | 2 | 2.0 | 8 | 1.00 |
| 15 | Bryce Dugan | Ohio | JR | DL | 1 | 1.0 | 19 | 1.00 |
| 15 | Lonnie Phelps | Miami (Oh) | SO | DL | 1 | 1.0 | 12 | 1.00 |
| 15 | Quadric Bullard | UCF | SO | DB | 1 | 1.0 | 12 | 1.00 |
| 15 | Marqez Bimage | California | SR | OLB | 1 | 1.0 | 11 | 1.00 |
| 15 | Jer'Zhan Newton | Illinois | FR | DL | 1 | 1.0 | 11 | 1.00 |
| 15 | Logan Hall | Houston | JR | DL | 1 | 1.0 | 10 | 1.00 |
| 15 | Quinyon Mitchell | Toledo | FR | CB | 1 | 1.0 | 8 | 1.00 |
| 15 | Jaylen Kelly-Powell | Akron | JR | S | 1 | 1.0 | 8 | 1.00 |
| 15 | Javon Solomon | Troy | FR | BAN | 1 | 1.0 | 8 | 1.00 |
| 15 | Xavier Gonsalves | U Mass | FR | DL | 1 | 1.0 | 7 | 1.00 |
| 15 | Josh Carr, Jr. | USM | JR | DL | 1 | 1.0 | 7 | 1.00 |
| 15 | Ryan Johnson | Akron | SO | DL | 1 | 1.0 | 7 | 1.00 |
| 15 | Tristan Allen | La Tech | JR | DL | 1 | 1.0 | 7 | 1.00 |
| 15 | Jacorey Crawford | Georgia St | SR | OLB | 1 | 1.0 | 7 | 1.00 |
| 15 | Marcus Haynes | ODU | JR | DE | 1 | 1.0 | 6 | 1.00 |
| 15 | Joe Ozougwu | Ark St | SR | DE | 1 | 1.0 | 6 | 1.00 |
| 15 | Amorie Morrison | ODU | FR | DE | 1 | 1.0 | 5 | 1.00 |
| 15 | Jonathan Jones | Toledo | SR | LB | 1 | 1.0 | 5 | 1.00 |
| 15 | Xavier Cullens | Memphis | SR | LB | 1 | 1.0 | 5 | 1.00 |
| 15 | Mike Brown | Miami (Oh) | SR | DB | 1 | 1.0 | 4 | 1.00 |
| 15 | Nate Givhan | Toledo | JR | OLB | 1 | 1.0 | 4 | 1.00 |
| 15 | Hayes Maples | USM | SO | LB | 1 | 1.0 | 4 | 1.00 |
| 15 | Wy'Kevious Thomas | USA | FR | DL | 1 | 1.0 | 4 | 1.00 |
| 15 | Jordan Veneziale | Georgia St | JR | ILB | 1 | 1.0 | 4 | 1.00 |
| 15 | Devan Barrett | Troy | JR | CB | 1 | 1.0 | 4 | 1.00 |
| 15 | Isaiah Gay | Illinois | SR | OLB | 1 | 1.0 | 3 | 1.00 |
| 15 | Kivon Bennett | Ark St | JR | DL | 1 | 1.0 | 1 | 1.00 |
| 15 | Daniel Grzesiak | Nevada | JR | DE | 1 | 1.0 | 1 | 1.00 |
| 57 | Isaiah McGuire | Missouri | JR | DL | 3 | 2.5 | 11 | 0.83 |
| 58 | Dallas Turner | Alabama | FR | LB | 5 | 4.0 | 26 | 0.80 |
| 58 | Derick Hall | Auburn | JR | EDG | 5 | 4.0 | 21 | 0.80 |
| 60 | Nakobe Dean | Georgia | JR | ILB | 6 | 4.5 | 34 | 0.75 |
| 60 | David Ojabo | Michigan | JR | LB | 4 | 3.0 | 29 | 0.75 |
| 60 | Damone Clark | LSU | SR | LB | 4 | 3.0 | 27 | 0.75 |
| 60 | Arnold Ebiketie | Penn State | SR | DE | 4 | 3.0 | 23 | 0.75 |
| 60 | Jermaine Johnson II | FSU | SR | DE | 4 | 3.0 | 17 | 0.75 |
| 60 | Smith Vilbert | Penn State | SO | DE | 4 | 3.0 | 17 | 0.75 |
| 60 | Scott Matlock | Boise St | JR | DT | 4 | 3.0 | 9 | 0.75 |
| 60 | Manny Jones | CSU | SR | DL | 2 | 1.5 | 11 | 0.75 |
| 60 | Mohamed Kamara | CSU | JR | LB | 2 | 1.5 | 9 | 0.75 |
| 69 | Christian Harris | Alabama | JR | LB | 5 | 3.5 | 39 | 0.70 |
| 69 | Micah McFadden | Indiana | SR | LB | 5 | 3.5 | 27 | 0.70 |
| 69 | Ryder Anderson | Indiana | SR | DL | 5 | 3.5 | 21 | 0.70 |
| 69 | Eyioma Uwazurike | Iowa State | SR | DE | 5 | 3.5 | 20 | 0.70 |
| 73 | Luiji Vilain | Wk Forest | SR | DL | 3 | 2.0 | 24 | 0.67 |
| 73 | Jasheen Davis | Wk Forest | FR | DL | 3 | 2.0 | 18 | 0.67 |
| 73 | Curtis Brooks | Cincinnati | SR | DL | 3 | 2.0 | 17 | 0.67 |
| 73 | SirVocea Dennis | Pittsburgh | JR | LB | 3 | 2.0 | 16 | 0.67 |
| 73 | Ochaun Mathis | TCU | JR | DE | 3 | 2.0 | 15 | 0.67 |
| 73 | Darius Hodges | Tulane | FR | JOK | 3 | 2.0 | 14 | 0.67 |
| 73 | Micheal Clemons | Texas A&M | SR | DL | 3 | 2.0 | 14 | 0.67 |
| 73 | Cullen Wick | Tulsa | SR | DL | 3 | 2.0 | 11 | 0.67 |
| 73 | Chance Campbell | Miss | SR | LB | 3 | 2.0 | 11 | 0.67 |
| 73 | Tony Bradford Jr. | Texas Tech | JR | DL | 3 | 2.0 | 10 | 0.67 |
| 73 | Nolan Turner | Clemson | SR | S | 3 | 2.0 | 10 | 0.67 |
| 73 | Noah Burks | Wisconsin | SR | OLB | 3 | 2.0 | 10 | 0.67 |
| 73 | Joel Dublanko | Cincinnati | SR | LB | 3 | 2.0 | 10 | 0.67 |
| 73 | Timmy Horne | Kansas St | SR | DT | 3 | 2.0 | 9 | 0.67 |
| 73 | Tyree Johnson | Texas A&M | SR | DL | 3 | 2.0 | 9 | 0.67 |
| 73 | C.J. Goetz | Wisconsin | JR | OLB | 3 | 2.0 | 9 | 0.67 |
| 73 | Etinosa Reuben | Clemson | SO | DT | 3 | 2.0 | 7 | 0.67 |
| 73 | Taijh Alston | WVU | JR | DL | 3 | 2.0 | 7 | 0.67 |
| 73 | Marcus Valdez | BC | SR | DE | 3 | 2.0 | 7 | 0.67 |
| 73 | Andrzej Hughes-Murray | Oregon St | SR | OLB | 3 | 2.0 | 7 | 0.67 |
| 73 | Felix Anudike-Uzomah | Kansas St | SO | DE | 3 | 2.0 | 6 | 0.67 |
| 73 | Habakkuk Baldonado | Pittsburgh | JR | DL | 3 | 2.0 | 5 | 0.67 |
| 95 | Cody Roscoe | Syracuse | SR | DL | 4 | 2.5 | 20 | 0.63 |
| 96 | Bryson Jackson | Baylor | SR | OLB | 5 | 3.0 | 24 | 0.60 |
| 96 | Nathaniel Watson | Miss St | JR | LB | 5 | 3.0 | 20 | 0.60 |
| 96 | Matthew Butler | Tennessee | SR | DL | 5 | 3.0 | 18 | 0.60 |
| 96 | Colby Wooden | Auburn | SO | DE | 5 | 3.0 | 15 | 0.60 |
| 96 | Phidarian Mathis | Alabama | SR | DL | 5 | 3.0 | 14 | 0.60 |
Note: To qualify, player must have played in 75% of his team's games.