2021 National Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Collin Oliver | Okla St | FR | DE | 4 | 6.0 | 46 | 1.50 |
| 2 | Terrel Bernard | Baylor | SR | LB | 4 | 5.5 | 35 | 1.38 |
| 3 | Will McDonald IV | Iowa State | JR | DE | 5 | 5.0 | 32 | 1.00 |
| 3 | Aidan Hutchinson | Michigan | SR | DE | 4 | 5.0 | 31 | 1.25 |
| 3 | Will Anderson Jr. | Alabama | SO | LB | 5 | 5.0 | 31 | 1.00 |
| 6 | Nakobe Dean | Georgia | JR | ILB | 6 | 4.5 | 34 | 0.75 |
| 6 | Tomon Fox | N Carolina | SR | LB | 4 | 4.5 | 25 | 1.13 |
| 6 | Nick Herbig | Wisconsin | SO | OLB | 3 | 4.5 | 22 | 1.50 |
| 6 | Keir Thomas | FSU | SR | DE | 4 | 4.5 | 19 | 1.13 |
| 10 | Byron Young | Tennessee | JR | DL | 4 | 4.0 | 35 | 1.00 |
| 10 | Dallas Turner | Alabama | FR | LB | 5 | 4.0 | 26 | 0.80 |
| 10 | Derick Hall | Auburn | JR | EDG | 5 | 4.0 | 21 | 0.80 |
| 13 | Christian Harris | Alabama | JR | LB | 5 | 3.5 | 39 | 0.70 |
| 13 | Travon Walker | Georgia | JR | DL | 6 | 3.5 | 28 | 0.58 |
| 13 | Micah McFadden | Indiana | SR | LB | 5 | 3.5 | 27 | 0.70 |
| 13 | Ryder Anderson | Indiana | SR | DL | 5 | 3.5 | 21 | 0.70 |
| 13 | Eyioma Uwazurike | Iowa State | SR | DE | 5 | 3.5 | 20 | 0.70 |
| 18 | Jacoby Windmon | UNLV | JR | ILB | 2 | 3.0 | 29 | 1.50 |
| 18 | David Ojabo | Michigan | JR | LB | 4 | 3.0 | 29 | 0.75 |
| 18 | Damone Clark | LSU | SR | LB | 4 | 3.0 | 27 | 0.75 |
| 18 | Bryson Jackson | Baylor | SR | OLB | 5 | 3.0 | 24 | 0.60 |
| 18 | Arnold Ebiketie | Penn State | SR | DE | 4 | 3.0 | 23 | 0.75 |
| 18 | Nolan Smith | Georgia | JR | OLB | 6 | 3.0 | 21 | 0.50 |
| 18 | Nathaniel Watson | Miss St | JR | LB | 5 | 3.0 | 20 | 0.60 |
| 18 | Matthew Butler | Tennessee | SR | DL | 5 | 3.0 | 18 | 0.60 |
| 18 | Jermaine Johnson II | FSU | SR | DE | 4 | 3.0 | 17 | 0.75 |
| 18 | Smith Vilbert | Penn State | SO | DE | 4 | 3.0 | 17 | 0.75 |
| 18 | Storey Jackson | Liberty | SR | LB | 2 | 3.0 | 16 | 1.50 |
| 18 | Brock Martin | Okla St | SR | DE | 3 | 3.0 | 16 | 1.00 |
| 18 | Colby Wooden | Auburn | SO | DE | 5 | 3.0 | 15 | 0.60 |
| 18 | Phidarian Mathis | Alabama | SR | DL | 5 | 3.0 | 14 | 0.60 |
| 18 | Nick Hampton | App St | JR | OLB | 2 | 3.0 | 10 | 1.50 |
| 18 | Scott Matlock | Boise St | JR | DT | 4 | 3.0 | 9 | 0.75 |
| 34 | Jeremy Lewis | ECU | SO | OLB | 2 | 2.5 | 20 | 1.25 |
| 34 | Cody Roscoe | Syracuse | SR | DL | 4 | 2.5 | 20 | 0.63 |
| 34 | TJ Franklin | Baylor | JR | DL | 5 | 2.5 | 16 | 0.50 |
| 34 | Isaiah McGuire | Missouri | JR | DL | 3 | 2.5 | 11 | 0.83 |
| 34 | Cory Durden | NC State | SR | DT | 2 | 2.5 | 9 | 1.25 |
| 34 | Scott Patchan | CSU | SR | DL | 2 | 2.5 | 8 | 1.25 |
| 34 | Adam Anderson | Georgia | SR | OLB | 3 | 2.5 | 7 | 0.83 |
| 41 | Nick Heninger | Utah State | SR | DE | 2 | 2.0 | 35 | 1.00 |
| 41 | Luiji Vilain | Wk Forest | SR | DL | 3 | 2.0 | 24 | 0.67 |
| 41 | Chris Ojoh | NMSU | JR | LB | 4 | 2.0 | 23 | 0.50 |
| 41 | Isaiah Foskey | Notre Dame | SO | DL | 2 | 2.0 | 21 | 1.00 |
| 41 | Sam Okuayinonu | Maryland | SR | DL | 4 | 2.0 | 20 | 0.50 |
| 41 | Ty Robinson | Nebraska | FR | DL | 5 | 2.0 | 20 | 0.40 |
| 41 | Neil Farrell Jr. | LSU | SR | DT | 4 | 2.0 | 19 | 0.50 |
| 41 | Jasheen Davis | Wk Forest | FR | DL | 3 | 2.0 | 18 | 0.67 |
| 41 | Mika Tafua | Utah | JR | DE | 5 | 2.0 | 18 | 0.40 |
| 41 | Eku Leota | Auburn | JR | EDG | 5 | 2.0 | 18 | 0.40 |
| 41 | Terrance Taylor | Toledo | JR | OLB | 1 | 2.0 | 17 | 2.00 |
| 41 | Curtis Brooks | Cincinnati | SR | DL | 3 | 2.0 | 17 | 0.67 |
| 41 | Xavier Thomas | Clemson | SR | DE | 4 | 2.0 | 17 | 0.50 |
| 41 | Jalen Pitre | Baylor | SR | S | 5 | 2.0 | 17 | 0.40 |
| 41 | Zach VanValkenburg | Iowa | SR | DL | 2 | 2.0 | 16 | 1.00 |
| 41 | SirVocea Dennis | Pittsburgh | JR | LB | 3 | 2.0 | 16 | 0.67 |
| 41 | Tyree Wilson | Texas Tech | JR | DL | 4 | 2.0 | 16 | 0.50 |
| 41 | Chantz Williams | Miami (Fl) | FR | DL | 4 | 2.0 | 16 | 0.50 |
| 41 | Malcolm Rodriguez | Okla St | SR | LB | 4 | 2.0 | 16 | 0.50 |
| 41 | Henry To'oTo'o | Alabama | JR | LB | 5 | 2.0 | 16 | 0.40 |
| 41 | Darian Varner | Temple | FR | DT | 2 | 2.0 | 15 | 1.00 |
| 41 | Ochaun Mathis | TCU | JR | DE | 3 | 2.0 | 15 | 0.67 |
| 41 | Aaron Brule | Miss St | JR | LB | 5 | 2.0 | 15 | 0.40 |
| 41 | Garret Fountain | SDSU | SO | LB | 2 | 2.0 | 14 | 1.00 |
| 41 | Joey Noble | New Mexico | SR | DE | 2 | 2.0 | 14 | 1.00 |
| 41 | Rick D'Abreu | ECU | SO | DL | 2 | 2.0 | 14 | 1.00 |
| 41 | Darius Hodges | Tulane | FR | JOK | 3 | 2.0 | 14 | 0.67 |
| 41 | Micheal Clemons | Texas A&M | SR | DL | 3 | 2.0 | 14 | 0.67 |
| 41 | Jalen Harris | Arizona | JR | DL | 4 | 2.0 | 14 | 0.50 |
| 41 | Garrett Nelson | Nebraska | SO | OLB | 5 | 2.0 | 14 | 0.40 |
| 41 | Myles Murphy | Clemson | SO | DE | 4 | 2.0 | 13 | 0.50 |
| 41 | Anthony Goodlow | Tulsa | JR | DL | 4 | 2.0 | 13 | 0.50 |
| 41 | DaMarcus Mitchell | Purdue | SR | DE | 4 | 2.0 | 13 | 0.50 |
| 41 | Micah Baskerville | LSU | SR | LB | 4 | 2.0 | 13 | 0.50 |
| 41 | Jeremy Banks | Tennessee | JR | LB | 5 | 2.0 | 13 | 0.40 |
| 41 | Vince Sanford | Air Force | JR | OLB | 2 | 2.0 | 12 | 1.00 |
| 41 | Mosiah Nasili-Kite | Maryland | JR | DL | 4 | 2.0 | 12 | 0.50 |
| 41 | Yasir Abdullah | Louisville | JR | LB | 5 | 2.0 | 12 | 0.40 |
| 41 | Robert Beal Jr. | Georgia | SR | OLB | 6 | 2.0 | 12 | 0.33 |
| 41 | Jalen Carter | Georgia | SO | DL | 6 | 2.0 | 12 | 0.33 |
| 41 | Ty Shelby | La-Monroe | SR | DE | 2 | 2.0 | 11 | 1.00 |
| 41 | Cullen Wick | Tulsa | SR | DL | 3 | 2.0 | 11 | 0.67 |
| 41 | Chance Campbell | Miss | SR | LB | 3 | 2.0 | 11 | 0.67 |
| 41 | Tony Bradford Jr. | Texas Tech | JR | DL | 3 | 2.0 | 10 | 0.67 |
| 41 | Nolan Turner | Clemson | SR | S | 3 | 2.0 | 10 | 0.67 |
| 41 | Noah Burks | Wisconsin | SR | OLB | 3 | 2.0 | 10 | 0.67 |
| 41 | Joel Dublanko | Cincinnati | SR | LB | 3 | 2.0 | 10 | 0.67 |
| 41 | Zakoby McClain | Auburn | SR | LB | 4 | 2.0 | 10 | 0.50 |
| 41 | Smoke Monday | Auburn | SR | S | 5 | 2.0 | 10 | 0.40 |
| 41 | Timmy Horne | Kansas St | SR | DT | 3 | 2.0 | 9 | 0.67 |
| 41 | Tyree Johnson | Texas A&M | SR | DL | 3 | 2.0 | 9 | 0.67 |
| 41 | C.J. Goetz | Wisconsin | JR | OLB | 3 | 2.0 | 9 | 0.67 |
| 41 | Antonio Grier | S Florida | SR | LB | 4 | 2.0 | 9 | 0.50 |
| 41 | R.J. Oben | Duke | SO | DE | 2 | 2.0 | 8 | 1.00 |
| 41 | George Karlaftis | Purdue | JR | DE | 4 | 2.0 | 8 | 0.50 |
| 41 | Etinosa Reuben | Clemson | SO | DT | 3 | 2.0 | 7 | 0.67 |
| 41 | Taijh Alston | WVU | JR | DL | 3 | 2.0 | 7 | 0.67 |
| 41 | Marcus Valdez | BC | SR | DE | 3 | 2.0 | 7 | 0.67 |
| 41 | Andrzej Hughes-Murray | Oregon St | SR | OLB | 3 | 2.0 | 7 | 0.67 |
| 41 | Trenton Simpson | Clemson | SO | LB | 4 | 2.0 | 7 | 0.50 |