2021 Pac-12 Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Washington | 1 | 55 | 220 | 72 | 275 | 3.82 | 275.0 |
| 2 | California | 1 | 61 | 312 | 65 | 373 | 5.74 | 373.0 |
| 3 | Oregon | 1 | 77 | 298 | 73 | 375 | 5.14 | 375.0 |
| 4 | UCLA | 2 | 140 | 698 | 165 | 838 | 5.08 | 419.0 |
| 5 | Stanford | 1 | 169 | 341 | 71 | 510 | 7.18 | 510.0 |
| 6 | Oregon State | 2 | 198 | 639 | 153 | 837 | 5.47 | 418.5 |
| 7 | Arizona State | 2 | 232 | 284 | 118 | 516 | 4.37 | 258.0 |
| 8 | USC | 3 | 404 | 797 | 210 | 1201 | 5.72 | 400.3 |
| 9 | Arizona | 2 | 416 | 390 | 132 | 806 | 6.11 | 403.0 |
| 10 | Utah | 2 | 435 | 193 | 140 | 628 | 4.49 | 314.0 |
| 11 | Washington State | 3 | 607 | 575 | 224 | 1182 | 5.28 | 394.0 |