2021 Pac-12 Conference Leaders Total Defense - Games in October Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | California | 4 | 492 | 769 | 242 | 1261 | 5.21 | 315.3 |
| 2 | Oregon | 4 | 506 | 945 | 306 | 1451 | 4.74 | 362.8 |
| 3 | USC | 4 | 557 | 1020 | 261 | 1577 | 6.04 | 394.3 |
| 4 | Arizona State | 4 | 585 | 1072 | 287 | 1657 | 5.77 | 414.3 |
| 5 | Utah | 4 | 646 | 1111 | 283 | 1757 | 6.21 | 439.3 |
| 6 | Oregon State | 4 | 711 | 1070 | 281 | 1781 | 6.34 | 445.3 |
| 7 | Washington | 4 | 764 | 482 | 253 | 1246 | 4.92 | 311.5 |
| 8 | Arizona | 4 | 768 | 860 | 267 | 1628 | 6.10 | 407.0 |
| 9 | UCLA | 5 | 793 | 1185 | 327 | 1978 | 6.05 | 395.6 |
| 10 | Stanford | 4 | 812 | 796 | 271 | 1608 | 5.93 | 402.0 |
| 11 | Colorado | 4 | 814 | 966 | 276 | 1780 | 6.45 | 445.0 |
| 12 | Washington State | 5 | 871 | 1005 | 342 | 1876 | 5.49 | 375.2 |