2021 Mid-American Conference Leaders Passes Defended - Games Lost Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Toledo | 6 | 4 | 25 | 29 | 4.83 |
| 2 | Miami (Ohio) | 6 | 5 | 18 | 23 | 3.83 |
| 3 | Central Michigan | 4 | 2 | 12 | 14 | 3.50 |
| 4 | Western Michigan | 5 | 0 | 16 | 16 | 3.20 |
| 5 | Buffalo | 8 | 1 | 24 | 25 | 3.13 |
| 6 | Eastern Michigan | 6 | 3 | 14 | 17 | 2.83 |
| 7 | Kent State | 7 | 6 | 13 | 19 | 2.71 |
| 8 | Ohio | 9 | 4 | 18 | 22 | 2.44 |
| 9 | Bowling Green | 8 | 3 | 15 | 18 | 2.25 |
| 10 | Ball State | 7 | 4 | 10 | 14 | 2.00 |
| 11 | Akron | 10 | 3 | 16 | 19 | 1.90 |
| 12 | Northern Illinois | 5 | 0 | 9 | 9 | 1.80 |