2021 Mid-American Conference Leaders Passes Defended - Games in October Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Toledo | 4 | 3 | 19 | 22 | 5.50 |
| 2 | Kent State | 4 | 4 | 14 | 18 | 4.50 |
| 2 | Eastern Michigan | 4 | 1 | 17 | 18 | 4.50 |
| 4 | Miami (Ohio) | 4 | 2 | 15 | 17 | 4.25 |
| 5 | Central Michigan | 4 | 1 | 15 | 16 | 4.00 |
| 5 | Northern Illinois | 4 | 1 | 15 | 16 | 4.00 |
| 7 | Ball State | 4 | 6 | 9 | 15 | 3.75 |
| 8 | Bowling Green | 5 | 3 | 12 | 15 | 3.00 |
| 9 | Ohio | 4 | 3 | 8 | 11 | 2.75 |
| 9 | Western Michigan | 4 | 0 | 11 | 11 | 2.75 |
| 11 | Buffalo | 5 | 1 | 12 | 13 | 2.60 |
| 12 | Akron | 4 | 4 | 5 | 9 | 2.25 |