2021 Mid-American Conference Leaders Rushing Defense - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 5 | 150 | 464 | 3.09 | 6 | 30.00 | 92.80 |
| 2 | Central Michigan | 6 | 209 | 809 | 3.87 | 10 | 34.83 | 134.83 |
| 3 | Miami (Ohio) | 7 | 244 | 950 | 3.89 | 10 | 34.86 | 135.71 |
| 4 | Ball State | 2 | 70 | 275 | 3.93 | 1 | 35.00 | 137.50 |
| 5 | Eastern Michigan | 5 | 180 | 916 | 5.09 | 10 | 36.00 | 183.20 |
| 6 | Kent State | 4 | 148 | 579 | 3.91 | 8 | 37.00 | 144.75 |
| 7 | Toledo | 6 | 233 | 865 | 3.71 | 2 | 38.83 | 144.17 |
| 8 | Buffalo | 7 | 280 | 1427 | 5.10 | 18 | 40.00 | 203.86 |
| 9 | Northern Illinois | 6 | 244 | 1455 | 5.96 | 13 | 40.67 | 242.50 |
| 10 | Akron | 7 | 290 | 1879 | 6.48 | 18 | 41.43 | 268.43 |
| 11 | Ohio | 6 | 261 | 1208 | 4.63 | 11 | 43.50 | 201.33 |
| 12 | Bowling Green | 5 | 224 | 835 | 3.73 | 13 | 44.80 | 167.00 |