2021 Mid-American Conference Leaders Opponent First Downs - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Buffalo | 4 | 51 | 42 | 7 | 100 | 25.0 |
| 2 | Bowling Green | 6 | 76 | 43 | 7 | 126 | 21.0 |
| 2 | Akron | 4 | 60 | 43 | 6 | 109 | 27.3 |
| 4 | Miami (Ohio) | 5 | 47 | 46 | 10 | 103 | 20.6 |
| 5 | Western Michigan | 7 | 68 | 47 | 15 | 130 | 18.6 |
| 6 | Central Michigan | 6 | 53 | 57 | 12 | 122 | 20.3 |
| 7 | Toledo | 6 | 52 | 70 | 16 | 138 | 23.0 |
| 7 | Ohio | 5 | 50 | 70 | 7 | 127 | 25.4 |
| 9 | Eastern Michigan | 7 | 80 | 71 | 14 | 165 | 23.6 |
| 10 | Northern Illinois | 7 | 74 | 81 | 8 | 163 | 23.3 |
| 11 | Ball State | 10 | 110 | 103 | 16 | 229 | 22.9 |
| 12 | Kent State | 9 | 111 | 122 | 20 | 253 | 28.1 |