2021 Mid-American Conference Leaders Opponent First Downs - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Ball State | 2 | 18 | 23 | 1 | 42 | 21.0 |
| 2 | Toledo | 6 | 44 | 45 | 14 | 103 | 17.2 |
| 2 | Bowling Green | 5 | 53 | 45 | 12 | 110 | 22.0 |
| 4 | Kent State | 4 | 37 | 47 | 8 | 92 | 23.0 |
| 5 | Northern Illinois | 6 | 79 | 48 | 6 | 133 | 22.2 |
| 6 | Western Michigan | 5 | 33 | 49 | 7 | 89 | 17.8 |
| 7 | Buffalo | 7 | 72 | 51 | 15 | 138 | 19.7 |
| 8 | Eastern Michigan | 5 | 60 | 54 | 5 | 119 | 23.8 |
| 9 | Akron | 7 | 96 | 61 | 6 | 163 | 23.3 |
| 10 | Ohio | 6 | 62 | 63 | 11 | 136 | 22.7 |
| 11 | Central Michigan | 6 | 49 | 70 | 11 | 130 | 21.7 |
| 12 | Miami (Ohio) | 7 | 51 | 79 | 13 | 143 | 20.4 |