2021 Big Ten Conference Leaders Opponent First Downs - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Indiana | 1 | 14 | 3 | 0 | 17 | 17.0 |
| 2 | Wisconsin | 4 | 17 | 30 | 8 | 55 | 13.8 |
| 3 | Nebraska | 3 | 21 | 29 | 4 | 54 | 18.0 |
| 4 | Ohio State | 4 | 23 | 31 | 9 | 63 | 15.8 |
| 5 | Rutgers | 5 | 29 | 35 | 11 | 75 | 15.0 |
| 6 | Michigan | 5 | 32 | 41 | 7 | 80 | 16.0 |
| 7 | Iowa | 6 | 33 | 50 | 6 | 89 | 14.8 |
| 8 | Michigan State | 4 | 38 | 42 | 8 | 88 | 22.0 |
| 9 | Purdue | 5 | 41 | 35 | 7 | 83 | 16.6 |
| 10 | Penn State | 5 | 42 | 40 | 12 | 94 | 18.8 |
| 11 | Maryland | 6 | 45 | 51 | 14 | 110 | 18.3 |
| 12 | Minnesota | 7 | 48 | 40 | 6 | 94 | 13.4 |
| 12 | Illinois | 5 | 48 | 47 | 9 | 104 | 20.8 |
| 14 | Northwestern | 5 | 52 | 47 | 3 | 102 | 20.4 |