2021 Penn State Nittany Lions Opponent First Down Split Stats through 01/10/2022
| Split | G | Rush | Pass | Penalty | Total |
|---|---|---|---|---|---|
| All Games | 13 | 124 | 121 | 29 | 274 |
| at Home | 7 | 59 | 57 | 14 | 130 |
| on Road/Neutral Site | 6 | 65 | 64 | 15 | 144 |
| in Wins | 7 | 51 | 73 | 17 | 141 |
| in Losses | 6 | 73 | 48 | 12 | 133 |
| vs. Conference | 9 | 84 | 84 | 21 | 189 |
| vs. Non-Conference | 4 | 40 | 37 | 8 | 85 |
| vs. Ranked (AP) | 5 | 53 | 45 | 9 | 107 |
| vs. Unranked (AP) | 8 | 71 | 76 | 20 | 167 |
| vs. FBS (I-A) | 12 | 120 | 111 | 28 | 259 |
| vs. FCS (I-AA) | 1 | 4 | 10 | 1 | 15 |
| vs. FBS Winning | 7 | 78 | 71 | 16 | 165 |
| vs. FBS Non-Winning | 5 | 42 | 40 | 12 | 94 |
| vs. FBS Power 5 | 11 | 115 | 99 | 24 | 238 |
| vs. FBS non-Power 5 | 1 | 5 | 12 | 4 | 21 |
| in August/September | 4 | 36 | 43 | 10 | 89 |
| in October | 4 | 36 | 33 | 9 | 78 |
| in November | 4 | 31 | 42 | 9 | 82 |
| in December/January | 1 | 21 | 3 | 1 | 25 |