2021 Big Ten Conference Leaders Long All Purpose Plays - Games at Home Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Jayden Reed | Mich St | JR | WR | 6 | 12 | 7 | 4 | 4 | 3 | 2 | 0 |
| 2 | Charlie Jones | Iowa | SR | WR | 7 | 7 | 3 | 2 | 2 | 2 | 1 | 1 |
| 2 | Samori Toure | Nebraska | SR | WR | 7 | 9 | 5 | 5 | 4 | 2 | 0 | 0 |
| 4 | Braelon Allen | Wisconsin | FR | RB | 7 | 5 | 2 | 2 | 1 | 1 | 0 | 0 |
| 4 | AJ Barner | Indiana | SO | TE | 6 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 4 | Ronnie Bell | Michigan | SR | WR | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 4 | Zavier Betts | Nebraska | FR | WR | 7 | 3 | 1 | 1 | 1 | 1 | 1 | 0 |
| 4 | Stephan Bracey | Wisconsin | SO | WR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 4 | Chase Brown | Illinois | SO | RB | 6 | 4 | 1 | 1 | 1 | 1 | 1 | 0 |
| 4 | Blake Corum | Michigan | SO | RB | 7 | 5 | 4 | 4 | 2 | 1 | 0 | 0 |
| 4 | Aron Cruickshank | Rutgers | JR | WR | 5 | 5 | 4 | 3 | 2 | 1 | 0 | 0 |
| 4 | Emeka Egbuka | Ohio State | FR | WR | 6 | 6 | 3 | 2 | 2 | 1 | 1 | 0 |
| 4 | Isaac Guerendo | Wisconsin | JR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 4 | A.J. Henning | Michigan | SO | WR | 7 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 4 | Jacolby Hewitt | Indiana | JR | WR | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 4 | Evan Hull | N'western | SO | RB | 6 | 6 | 2 | 1 | 1 | 1 | 1 | 1 |
| 4 | Cornelius Johnson | Michigan | JR | WR | 7 | 4 | 2 | 2 | 1 | 1 | 1 | 0 |
| 4 | KeAndre Lambert-Smith | Penn State | SO | WR | 7 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 4 | Adrian Martinez | Nebraska | JR | QB | 6 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 4 | D.J. Matthews Jr. | Indiana | SR | WR | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 4 | Garrett Wilson | Ohio State | JR | WR | 7 | 4 | 3 | 3 | 1 | 1 | 0 | 0 |
| 4 | Craig Young | Ohio State | SO | SAF | 7 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |