2021 American Athletic Conference Leaders Passes Defended - Games in December/January Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | UCF | 1 | 0 | 6 | 6 | 6.00 |
| 2 | Navy | 1 | 0 | 5 | 5 | 5.00 |
| 3 | Tulsa | 1 | 1 | 3 | 4 | 4.00 |
| 4 | Cincinnati | 2 | 2 | 4 | 6 | 3.00 |
| 5 | Houston | 2 | 0 | 3 | 3 | 1.50 |