2021 American Athletic Conference Leaders Fumbles Lost - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | Houston | 13 | 11 | 2 | 18.18 |
| 2 | Navy | 9 | 15 | 4 | 26.67 |
| 3 | UCF | 12 | 12 | 5 | 41.67 |
| 4 | South Florida | 8 | 13 | 6 | 46.15 |
| 5 | SMU | 10 | 10 | 5 | 50.00 |
| 5 | East Carolina | 10 | 14 | 7 | 50.00 |
| 7 | Tulsa | 9 | 10 | 6 | 60.00 |
| 8 | Memphis | 11 | 13 | 8 | 61.54 |
| 9 | Tulane | 8 | 8 | 5 | 62.50 |
| 10 | Cincinnati | 11 | 13 | 9 | 69.23 |
| 11 | Temple | 10 | 14 | 10 | 71.43 |