2021 American Athletic Conference Leaders Tackles For Loss - Games Lost Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | East Carolina | 5 | 37.0 | 160 | 7.40 |
| 2 | Tulane | 10 | 70.0 | 253 | 7.00 |
| 3 | Temple | 9 | 60.0 | 199 | 6.67 |
| 4 | Memphis | 6 | 36.0 | 113 | 6.00 |
| 4 | Cincinnati | 1 | 6.0 | 15 | 6.00 |
| 6 | Tulsa | 6 | 30.0 | 86 | 5.00 |
| 7 | Navy | 8 | 39.0 | 123 | 4.88 |
| 8 | UCF | 4 | 19.0 | 63 | 4.75 |
| 9 | SMU | 4 | 18.0 | 53 | 4.50 |
| 10 | South Florida | 10 | 43.0 | 129 | 4.30 |
| 11 | Houston | 2 | 8.0 | 40 | 4.00 |