2021 American Athletic Conference Leaders Tackles For Loss - Games Won Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Cincinnati | 13 | 95.0 | 359 | 7.31 |
| 2 | Houston | 12 | 90.0 | 362 | 7.50 |
| 3 | UCF | 9 | 68.0 | 299 | 7.56 |
| 4 | SMU | 8 | 46.0 | 193 | 5.75 |
| 5 | Tulsa | 7 | 43.0 | 143 | 6.14 |
| 6 | East Carolina | 7 | 34.0 | 111 | 4.86 |
| 7 | Memphis | 6 | 29.0 | 160 | 4.83 |
| 8 | Navy | 4 | 23.0 | 91 | 5.75 |
| 9 | Temple | 3 | 19.0 | 76 | 6.33 |
| 10 | Tulane | 2 | 18.0 | 98 | 9.00 |
| 11 | USF | 2 | 6.0 | 24 | 3.00 |