2021 American Athletic Conference Leaders Tackles For Loss - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | University of Houston | 5 | 41.0 | 171 | 8.20 |
| 2 | The University of Tulsa | 5 | 33.0 | 110 | 6.60 |
| 3 | Tulane University | 4 | 32.0 | 139 | 8.00 |
| 3 | University of Cincinnati | 5 | 32.0 | 82 | 6.40 |
| 5 | Temple University | 4 | 30.0 | 103 | 7.50 |
| 6 | East Carolina University | 4 | 29.0 | 103 | 7.25 |
| 6 | University of Central Florida | 5 | 29.0 | 96 | 5.80 |
| 8 | University of Memphis | 4 | 22.0 | 81 | 5.50 |
| 9 | U.S. Naval Academy | 4 | 19.0 | 68 | 4.75 |
| 10 | Southern Methodist University | 4 | 16.0 | 66 | 4.00 |
| 11 | University of South Florida | 4 | 11.0 | 33 | 2.75 |