2021 American Athletic Conference Leaders Fumbles Lost - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | Tulane | 2 | 5 | 2 | 40.00 |
| 1 | Cincinnati | 5 | 5 | 3 | 60.00 |
| 3 | Houston | 8 | 6 | 0 | 0.00 |
| 3 | Navy | 2 | 6 | 1 | 16.67 |
| 3 | East Carolina | 5 | 6 | 3 | 50.00 |
| 3 | Memphis | 4 | 6 | 4 | 66.67 |
| 7 | South Florida | 3 | 7 | 2 | 28.57 |
| 7 | SMU | 7 | 7 | 5 | 71.43 |
| 9 | Tulsa | 7 | 8 | 5 | 62.50 |
| 10 | UCF | 8 | 9 | 4 | 44.44 |
| 10 | Temple | 6 | 9 | 6 | 66.67 |