2021 American Athletic Conference Leaders Total Offense - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 8 | 1469 | 1936 | 479 | 3405 | 7.11 | 425.6 |
| 2 | SMU | 4 | 531 | 1059 | 295 | 1590 | 5.39 | 397.5 |
| 3 | Tulsa | 5 | 654 | 1314 | 368 | 1968 | 5.35 | 393.6 |
| 4 | UCF | 4 | 699 | 862 | 280 | 1561 | 5.58 | 390.3 |
| 5 | Memphis | 7 | 647 | 2047 | 506 | 2694 | 5.32 | 384.9 |
| 6 | East Carolina | 6 | 645 | 1567 | 439 | 2212 | 5.04 | 368.7 |
| 7 | Houston | 5 | 471 | 1266 | 349 | 1737 | 4.98 | 347.4 |
| 8 | Tulane | 9 | 1188 | 1913 | 603 | 3101 | 5.14 | 344.6 |
| 9 | South Florida | 8 | 1004 | 1679 | 528 | 2683 | 5.08 | 335.4 |
| 10 | Navy | 10 | 2301 | 566 | 651 | 2867 | 4.40 | 286.7 |
| 11 | Temple | 5 | 543 | 667 | 314 | 1210 | 3.85 | 242.0 |