2021 American Athletic Conference Leaders Total Offense - Games in October Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tanner Mordecai | SMU | JR | QB | 4 | 55 | 1357 | 185 | 1412 | 7.63 | 353.0 |
| 2 | Clayton Tune | Houston | JR | QB | 4 | -45 | 1110 | 148 | 1065 | 7.20 | 266.3 |
| 3 | Desmond Ridder | Cincinnati | SR | QB | 5 | 99 | 1099 | 177 | 1198 | 6.77 | 239.6 |
| 4 | Holton Ahlers | ECU | JR | QB | 4 | 94 | 1005 | 171 | 1099 | 6.43 | 274.8 |
| 5 | Seth Henigan | Memphis | FR | QB | 3 | 62 | 983 | 131 | 1045 | 7.98 | 348.3 |
| 6 | Davis Brin | Tulsa | JR | QB | 4 | -4 | 861 | 147 | 857 | 5.83 | 214.3 |
| 7 | Mikey Keene | UCF | FR | QB | 5 | -5 | 805 | 140 | 800 | 5.71 | 160.0 |
| 8 | D'Wan Mathis | Temple | FR | QB | 4 | 76 | 746 | 154 | 822 | 5.34 | 205.5 |
| 9 | Michael Pratt | Tulane | FR | QB | 4 | 0 | 716 | 123 | 716 | 5.82 | 179.0 |
| 10 | Timmy McClain | S Florida | FR | QB | 3 | 84 | 442 | 93 | 526 | 5.66 | 175.3 |
| 11 | Tai Lavatai | Navy | SO | QB | 5 | 224 | 265 | 134 | 489 | 3.65 | 97.8 |
| 12 | Katravis Marsh | S Florida | SO | QB | 2 | 20 | 217 | 40 | 237 | 5.93 | 118.5 |
| 13 | Peter Parrish | Memphis | SO | QB | 2 | 60 | 215 | 70 | 275 | 3.93 | 137.5 |
| 14 | Kai Horton | Tulane | FR | QB | 3 | -16 | 79 | 26 | 63 | 2.42 | 21.0 |
| 15 | Justin Lynch | Temple | FR | QB | 3 | 56 | 76 | 20 | 132 | 6.60 | 44.0 |
| 16 | Ike Ogbogu | Houston | JR | QB | 1 | 0 | 20 | 6 | 20 | 3.33 | 20.0 |
| 17 | Joey Gatewood | UCF | JR | QB | 5 | 119 | 17 | 25 | 136 | 5.44 | 27.2 |
| 18 | Chance Warren | Navy | SR | SB | 5 | 163 | 16 | 25 | 179 | 7.16 | 35.8 |
| 19 | Christian Daniels | Tulane | SO | WR | 3 | 29 | 14 | 6 | 43 | 7.17 | 14.3 |
| 19 | Mason Garcia | ECU | FR | QB | 3 | 6 | 14 | 5 | 20 | 4.00 | 6.7 |
| 21 | Ryan Wright | Tulane | SR | P | 4 | 0 | 12 | 2 | 12 | 6.00 | 3.0 |
| 22 | Preston Stone | SMU | FR | QB | 1 | 2 | 11 | 3 | 13 | 4.33 | 13.0 |
| 23 | Cade Fortin | S Florida | SO | QB | 2 | 11 | 9 | 2 | 20 | 10.00 | 10.0 |
| 24 | Kenny Scribner | S Florida | SO | P | 4 | 0 | 7 | 1 | 7 | 7.00 | 1.8 |
| 25 | Evan Prater | Cincinnati | FR | QB | 4 | 9 | 4 | 3 | 13 | 4.33 | 3.3 |