2021 American Athletic Conference Leaders Rushing - From Own 40 to Opponent's 40 Yard Line through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jerome Ford | Cincinnati | JR | RB | 12 | 42 | 311 | 7.40 | 2 | 43 | 18 | 12 | 4 |
| 2 | Alton McCaskill | Houston | FR | RB | 14 | 52 | 290 | 5.58 | 0 | 24 | 16 | 11 | 3 |
| 3 | Keaton Mitchell | ECU | FR | RB | 10 | 47 | 268 | 5.70 | 1 | 57 | 11 | 7 | 2 |
| 4 | Tyjae Spears | Tulane | FR | RB | 9 | 32 | 253 | 7.91 | 1 | 47 | 14 | 9 | 3 |
| 4 | Shamari Brooks | Tulsa | SR | RB | 13 | 44 | 253 | 5.75 | 0 | 37 | 11 | 8 | 1 |
| 6 | Anthony Watkins | Tulsa | SO | RB | 9 | 24 | 222 | 9.25 | 1 | 44 | 11 | 9 | 2 |
| 7 | Tre Siggers | SMU | SR | RB | 11 | 41 | 216 | 5.27 | 0 | 33 | 11 | 5 | 2 |
| 8 | Johnny Richardson | UCF | SO | RB | 10 | 24 | 202 | 8.42 | 0 | 38 | 9 | 7 | 4 |
| 9 | Deneric Prince | Tulsa | JR | RB | 8 | 25 | 190 | 7.60 | 1 | 59 | 6 | 5 | 2 |
| 10 | Desmond Ridder | Cincinnati | SR | QB | 13 | 34 | 177 | 5.21 | 1 | 40 | 11 | 7 | 3 |
| 11 | Ulysses Bentley IV | SMU | SO | RB | 8 | 21 | 176 | 8.38 | 1 | 56 | 10 | 6 | 2 |
| 11 | Rahjai Harris | ECU | FR | RB | 11 | 44 | 176 | 4.00 | 0 | 21 | 10 | 5 | 1 |
| 13 | Isaac Ruoss | Navy | SR | FB | 11 | 46 | 170 | 3.70 | 0 | 12 | 11 | 2 | 0 |
| 14 | Isaiah Bowser | UCF | SR | RB | 8 | 37 | 162 | 4.38 | 0 | 24 | 10 | 4 | 1 |
| 15 | Jaren Mangham | S Florida | JR | RB | 10 | 41 | 155 | 3.78 | 0 | 24 | 14 | 4 | 1 |
| 16 | Tai Lavatai | Navy | SO | QB | 9 | 47 | 143 | 3.04 | 0 | 14 | 14 | 4 | 0 |
| 17 | Rodrigues Clark | Memphis | JR | RB | 7 | 23 | 141 | 6.13 | 0 | 21 | 9 | 5 | 1 |
| 18 | Mark-Antony Richards | UCF | SO | RB | 6 | 12 | 133 | 11.08 | 1 | 58 | 5 | 3 | 2 |
| 19 | Cameron Carroll | Tulane | SO | RB | 10 | 24 | 125 | 5.21 | 0 | 47 | 6 | 4 | 1 |
| 20 | Ryan Montgomery | Cincinnati | JR | RB | 8 | 15 | 117 | 7.80 | 1 | 55 | 5 | 2 | 1 |
| 20 | Ta'Zhawn Henry | Houston | JR | RB | 9 | 29 | 117 | 4.03 | 0 | 21 | 2 | 3 | 1 |
| 22 | Kelley Joiner | S Florida | JR | RB | 5 | 17 | 114 | 6.71 | 0 | 25 | 8 | 6 | 1 |
| 23 | Carlinos Acie | Navy | SR | SB | 6 | 13 | 104 | 8.00 | 0 | 15 | 4 | 4 | 0 |
| 24 | Holton Ahlers | ECU | JR | QB | 11 | 33 | 98 | 2.97 | 0 | 19 | 11 | 6 | 0 |
| 25 | Xavier Arline | Navy | SO | QB | 3 | 9 | 95 | 10.56 | 1 | 40 | 4 | 3 | 1 |
| 26 | Tanner Mordecai | SMU | JR | QB | 10 | 21 | 93 | 4.43 | 0 | 20 | 7 | 5 | 1 |
| 27 | Ryan O'Keefe | UCF | JR | WR | 5 | 7 | 87 | 12.43 | 0 | 34 | 5 | 3 | 1 |
| 27 | Timmy McClain | S Florida | FR | QB | 11 | 33 | 87 | 2.64 | 0 | 21 | 7 | 6 | 1 |
| 29 | Brandon Thomas | Memphis | FR | RB | 6 | 17 | 85 | 5.00 | 0 | 34 | 3 | 1 | 1 |
| 30 | James Harris II | Navy | SR | FB | 9 | 20 | 81 | 4.05 | 0 | 13 | 8 | 1 | 0 |
| 31 | Tayvon Ruley | Temple | SR | RB | 5 | 10 | 78 | 7.80 | 0 | 19 | 4 | 4 | 0 |
| 31 | Tyler Lavine | SMU | JR | RB | 7 | 11 | 78 | 7.09 | 0 | 16 | 5 | 4 | 0 |
| 33 | Justin Lynch | Temple | FR | QB | 6 | 18 | 75 | 4.17 | 0 | 33 | 4 | 1 | 1 |
| 34 | Jayden Umbarger | Navy | SO | WR | 5 | 5 | 74 | 14.80 | 0 | 32 | 3 | 3 | 2 |
| 35 | Edward Saydee | Temple | FR | RB | 7 | 21 | 69 | 3.29 | 0 | 11 | 5 | 2 | 0 |
| 36 | Ethan Wright | Cincinnati | SO | RB | 4 | 7 | 66 | 9.43 | 1 | 58 | 2 | 1 | 1 |
| 37 | Steven Anderson | Tulsa | JR | RB | 5 | 13 | 65 | 5.00 | 0 | 12 | 4 | 1 | 0 |
| 38 | Mulbah Car | Houston | SR | RB | 6 | 11 | 63 | 5.73 | 0 | 14 | 3 | 2 | 0 |
| 39 | Dillon Gabriel | UCF | JR | QB | 3 | 9 | 60 | 6.67 | 1 | 44 | 3 | 2 | 2 |
| 40 | Marquavius Weaver | Memphis | SR | RB | 7 | 13 | 55 | 4.23 | 0 | 16 | 4 | 3 | 0 |
| 40 | Clayton Tune | Houston | JR | QB | 13 | 41 | 55 | 1.34 | 0 | 42 | 7 | 5 | 2 |
| 42 | Evan Prater | Cincinnati | FR | QB | 3 | 4 | 50 | 12.50 | 0 | 33 | 1 | 1 | 1 |
| 42 | Iverson Celestine | Tulane | FR | RB | 2 | 6 | 50 | 8.33 | 0 | 26 | 3 | 3 | 1 |
| 44 | Asa Martin | Memphis | JR | RB | 4 | 9 | 42 | 4.67 | 0 | 13 | 3 | 1 | 0 |
| 45 | Seth Henigan | Memphis | FR | QB | 9 | 25 | 40 | 1.60 | 0 | 12 | 4 | 3 | 0 |
| 46 | Donavan Mutin | Houston | JR | LB | 1 | 1 | 38 | 38.00 | 0 | 38 | 1 | 1 | 1 |
| 47 | Brian Battie | S Florida | SO | RB | 8 | 10 | 36 | 3.60 | 0 | 12 | 3 | 1 | 0 |
| 48 | Ra'Von Bonner | Temple | JR | RB | 4 | 9 | 33 | 3.67 | 0 | 7 | 1 | 0 | 0 |
| 48 | Chance Warren | Navy | SR | SB | 7 | 12 | 33 | 2.75 | 0 | 14 | 1 | 1 | 0 |
| 50 | Joey Gatewood | UCF | JR | QB | 5 | 6 | 32 | 5.33 | 0 | 14 | 1 | 1 | 0 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | |||||||||||||