2021 Atlantic Coast Conference Leaders Rushing Offense - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 12 | 470 | 2610 | 5.55 | 27 | 39.17 | 217.50 |
| 2 | North Carolina | 12 | 473 | 2463 | 5.21 | 27 | 39.42 | 205.25 |
| 3 | Virginia Tech | 12 | 499 | 2299 | 4.61 | 15 | 41.58 | 191.58 |
| 4 | Syracuse | 11 | 449 | 2276 | 5.07 | 22 | 40.82 | 206.91 |
| 5 | Wake Forest | 13 | 534 | 2086 | 3.91 | 27 | 41.08 | 160.46 |
| 6 | Duke | 11 | 486 | 2016 | 4.15 | 16 | 44.18 | 183.27 |
| 7 | Clemson | 12 | 453 | 1942 | 4.29 | 21 | 37.75 | 161.83 |
| 8 | Florida State | 11 | 409 | 1933 | 4.73 | 20 | 37.18 | 175.73 |
| 9 | Georgia Tech | 11 | 408 | 1869 | 4.58 | 14 | 37.09 | 169.91 |
| 10 | Pittsburgh | 13 | 476 | 1837 | 3.86 | 21 | 36.62 | 141.31 |
| 11 | Boston College | 11 | 444 | 1793 | 4.04 | 18 | 40.36 | 163.00 |
| 12 | North Carolina State | 11 | 341 | 1296 | 3.80 | 8 | 31.00 | 117.82 |
| 13 | Virginia | 11 | 307 | 1279 | 4.17 | 18 | 27.91 | 116.27 |
| 14 | Miami (Florida) | 11 | 370 | 1210 | 3.27 | 15 | 33.64 | 110.00 |