2021 Atlantic Coast Conference Leaders Rushing Offense - When The Game Is Tied through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 11 | 112 | 681 | 6.08 | 8 | 51 | 29 | 23 | 11 |
| 2 | Clemson | 12 | 118 | 518 | 4.39 | 6 | 59 | 25 | 16 | 3 |
| 3 | Virginia Tech | 12 | 97 | 464 | 4.78 | 4 | 20 | 27 | 17 | 1 |
| 4 | Syracuse | 11 | 124 | 462 | 3.73 | 3 | 54 | 25 | 13 | 3 |
| 5 | Wake Forest | 13 | 90 | 412 | 4.58 | 4 | 48 | 19 | 11 | 3 |
| 6 | Pittsburgh | 13 | 73 | 380 | 5.21 | 5 | 58 | 19 | 12 | 2 |
| 7 | North Carolina State | 10 | 112 | 376 | 3.36 | 2 | 42 | 20 | 7 | 2 |
| 8 | Boston College | 12 | 86 | 326 | 3.79 | 6 | 22 | 21 | 9 | 2 |
| 9 | North Carolina | 12 | 60 | 320 | 5.33 | 4 | 51 | 19 | 13 | 4 |
| 10 | Georgia Tech | 11 | 51 | 260 | 5.10 | 1 | 26 | 14 | 10 | 2 |
| 11 | Florida State | 9 | 58 | 252 | 4.34 | 2 | 33 | 14 | 8 | 4 |
| 12 | Duke | 9 | 58 | 248 | 4.28 | 3 | 57 | 13 | 3 | 2 |
| 13 | Virginia | 10 | 48 | 189 | 3.94 | 3 | 27 | 8 | 6 | 2 |
| 14 | Miami (Florida) | 8 | 37 | 156 | 4.22 | 1 | 20 | 11 | 5 | 1 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||