2021 Atlantic Coast Conference Leaders Fumbles Lost - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | Virginia | 8 | 14 | 4 | 28.57 |
| 2 | Florida State | 8 | 11 | 4 | 36.36 |
| 2 | Louisville | 8 | 11 | 4 | 36.36 |
| 4 | Wake Forest | 11 | 8 | 3 | 37.50 |
| 5 | Georgia Tech | 8 | 10 | 4 | 40.00 |
| 5 | Syracuse | 8 | 10 | 4 | 40.00 |
| 7 | Clemson | 9 | 14 | 6 | 42.86 |
| 8 | Boston College | 9 | 9 | 4 | 44.44 |
| 8 | North Carolina | 9 | 9 | 4 | 44.44 |
| 10 | Virginia Tech | 11 | 12 | 6 | 50.00 |
| 11 | Miami (Florida) | 8 | 7 | 4 | 57.14 |
| 12 | North Carolina State | 10 | 5 | 3 | 60.00 |
| 12 | Pittsburgh | 11 | 10 | 6 | 60.00 |
| 14 | Duke | 10 | 15 | 10 | 66.67 |