2021 Atlantic Coast Conference Leaders Fumbles Lost - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | Wake Forest | 4 | 4 | 1 | 25.00 |
| 1 | Florida State | 4 | 8 | 2 | 25.00 |
| 3 | Virginia Tech | 5 | 7 | 2 | 28.57 |
| 4 | Louisville | 5 | 6 | 2 | 33.33 |
| 5 | Clemson | 5 | 5 | 2 | 40.00 |
| 5 | Syracuse | 4 | 5 | 2 | 40.00 |
| 7 | North Carolina | 4 | 2 | 1 | 50.00 |
| 7 | Virginia | 4 | 4 | 2 | 50.00 |
| 9 | Georgia Tech | 4 | 5 | 3 | 60.00 |
| 10 | North Carolina State | 4 | 3 | 2 | 66.67 |
| 10 | Pittsburgh | 5 | 6 | 4 | 66.67 |
| 12 | Duke | 4 | 7 | 5 | 71.43 |
| 13 | Boston College | 4 | 2 | 2 | 100.00 |
| 13 | Miami (Florida) | 4 | 3 | 3 | 100.00 |