2021 Atlantic Coast Conference Leaders Total Offense - Games Lost Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Virginia | 6 | 526 | 2434 | 438 | 2960 | 6.76 | 493.3 |
| 2 | Pittsburgh | 3 | 247 | 1104 | 192 | 1351 | 7.04 | 450.3 |
| 3 | Wake Forest | 3 | 335 | 981 | 250 | 1316 | 5.26 | 438.7 |
| 4 | Louisville | 7 | 1410 | 1574 | 472 | 2984 | 6.32 | 426.3 |
| 5 | North Carolina State | 3 | 219 | 1021 | 217 | 1240 | 5.71 | 413.3 |
| 6 | North Carolina | 7 | 1178 | 1706 | 466 | 2884 | 6.19 | 412.0 |
| 7 | Duke | 9 | 1526 | 1894 | 684 | 3420 | 5.00 | 380.0 |
| 8 | Miami (Florida) | 5 | 508 | 1350 | 364 | 1858 | 5.10 | 371.6 |
| 9 | Georgia Tech | 9 | 1466 | 1696 | 601 | 3162 | 5.26 | 351.3 |
| 10 | Florida State | 7 | 1008 | 1397 | 464 | 2405 | 5.18 | 343.6 |
| 11 | Syracuse | 7 | 1158 | 1021 | 442 | 2179 | 4.93 | 311.3 |
| 12 | Virginia Tech | 7 | 1094 | 1079 | 457 | 2173 | 4.75 | 310.4 |
| 13 | Boston College | 6 | 660 | 993 | 399 | 1653 | 4.14 | 275.5 |
| 14 | Clemson | 3 | 269 | 440 | 171 | 709 | 4.15 | 236.3 |