2021 Atlantic Coast Conference Leaders Rushing Offense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Wake Forest | 10 | 433 | 1594 | 3.68 | 20 | 43.30 | 159.40 |
| 2 | North Carolina | 9 | 365 | 1910 | 5.23 | 19 | 40.56 | 212.22 |
| 3 | Duke | 8 | 337 | 1173 | 3.48 | 5 | 42.13 | 146.63 |
| 4 | Pittsburgh | 9 | 334 | 1339 | 4.01 | 13 | 37.11 | 148.78 |
| 5 | Virginia Tech | 8 | 333 | 1720 | 5.17 | 7 | 41.63 | 215.00 |
| 6 | Louisville | 8 | 322 | 1888 | 5.86 | 18 | 40.25 | 236.00 |
| 6 | Syracuse | 8 | 322 | 1698 | 5.27 | 15 | 40.25 | 212.25 |
| 8 | Boston College | 8 | 312 | 1089 | 3.49 | 9 | 39.00 | 136.13 |
| 9 | Clemson | 8 | 304 | 1418 | 4.66 | 14 | 38.00 | 177.25 |
| 10 | Georgia Tech | 8 | 287 | 1372 | 4.78 | 12 | 35.88 | 171.50 |
| 11 | Florida State | 8 | 283 | 1159 | 4.10 | 10 | 35.38 | 144.88 |
| 12 | Miami (Florida) | 8 | 272 | 896 | 3.29 | 13 | 34.00 | 112.00 |
| 13 | North Carolina State | 8 | 245 | 802 | 3.27 | 2 | 30.63 | 100.25 |
| 14 | Virginia | 8 | 219 | 848 | 3.87 | 14 | 27.38 | 106.00 |