2021 Atlantic Coast Conference Leaders Scoring Defense - Games Lost Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 3 | 8 | 3 | 7 | 0 | 0 | 64 | 21.3 |
| 2 | North Carolina State | 3 | 13 | 3 | 13 | 0 | 0 | 100 | 33.3 |
| 3 | Pittsburgh | 3 | 15 | 3 | 12 | 1 | 0 | 113 | 37.7 |
| 4 | Wake Forest | 3 | 19 | 6 | 19 | 0 | 0 | 151 | 50.3 |
| 5 | Boston College | 6 | 20 | 8 | 20 | 0 | 2 | 168 | 28.0 |
| 6 | Miami (Florida) | 5 | 22 | 10 | 20 | 2 | 1 | 188 | 37.6 |
| 7 | Florida State | 7 | 27 | 7 | 24 | 1 | 0 | 209 | 29.9 |
| 8 | Syracuse | 7 | 27 | 11 | 23 | 1 | 0 | 220 | 31.4 |
| 9 | Virginia Tech | 7 | 31 | 7 | 28 | 1 | 0 | 237 | 33.9 |
| 10 | North Carolina | 7 | 30 | 11 | 26 | 2 | 0 | 243 | 34.7 |
| 11 | Louisville | 7 | 31 | 13 | 30 | 0 | 0 | 255 | 36.4 |
| 12 | Virginia | 6 | 34 | 9 | 34 | 0 | 1 | 267 | 44.5 |
| 13 | Georgia Tech | 9 | 42 | 14 | 40 | 1 | 0 | 336 | 37.3 |
| 14 | Duke | 9 | 51 | 16 | 50 | 0 | 0 | 404 | 44.9 |