2021 Atlantic Coast Conference Leaders Long All Purpose Plays - Games in October Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Jahmyr Gibbs | Ga Tech | FR | RB | 4 | 6 | 4 | 4 | 4 | 3 | 0 | 0 |
| 2 | Tyler Harrell | Louisville | SO | WR | 4 | 2 | 2 | 2 | 2 | 2 | 1 | 1 |
| 2 | Tré Turner | Va Tech | JR | WR | 4 | 3 | 3 | 2 | 2 | 0 | 0 | 0 |
| 2 | Dontayvion Wicks | Virginia | SO | WR | 4 | 2 | 2 | 2 | 2 | 2 | 0 | 0 |
| 5 | Jarvis Brownlee, Jr. | FSU | FR | DB | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Jalon Calhoun | Duke | JR | WR | 4 | 3 | 1 | 1 | 1 | 1 | 1 | 0 |
| 5 | Ty Chandler | N Carolina | SR | RB | 4 | 3 | 3 | 3 | 1 | 1 | 0 | 0 |
| 5 | Josh Downs | N Carolina | SO | WR | 4 | 6 | 3 | 1 | 1 | 0 | 0 | 0 |
| 5 | Courtney Jackson | Syracuse | FR | WR | 5 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Jaylan Knighton | Miami (Fl) | FR | RB | 3 | 3 | 3 | 2 | 1 | 0 | 0 | 0 |
| 5 | Phil Mafah | Clemson | FR | RB | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Trey Morrison | N Carolina | SR | DB | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Trebor Pena | Syracuse | FR | WR | 4 | 3 | 2 | 2 | 1 | 0 | 0 | 0 |
| 5 | A.T. Perry | Wk Forest | SO | WR | 4 | 6 | 4 | 3 | 1 | 0 | 0 | 0 |
| 5 | Charleston Rambo | Miami (Fl) | JR | WR | 3 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Traveon Redd | Wk Forest | SR | DB | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 5 | Jaquarii Roberson | Wk Forest | JR | WR | 4 | 6 | 4 | 1 | 1 | 1 | 0 | 0 |
| 5 | Thayer Thomas | NC State | JR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Lawrance Toafili | FSU | FR | RB | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Treshaun Ward | FSU | FR | RB | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Jordan Watkins | Louisville | FR | WR | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Ke'Shawn Williams | Wk Forest | FR | WR | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |