2021 Mountain West Conference Leaders Total Defense - Games in August/September Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | San Diego State | 4 | 182 | 975 | 284 | 1157 | 4.07 | 289.3 |
| 2 | New Mexico | 4 | 305 | 1000 | 267 | 1305 | 4.89 | 326.3 |
| 3 | Air Force | 4 | 400 | 802 | 238 | 1202 | 5.05 | 300.5 |
| 4 | Colorado State | 4 | 411 | 956 | 267 | 1367 | 5.12 | 341.8 |
| 5 | Fresno State | 5 | 543 | 1024 | 323 | 1567 | 4.85 | 313.4 |
| 6 | San Jose State | 4 | 545 | 837 | 279 | 1382 | 4.95 | 345.5 |
| 7 | Nevada | 3 | 563 | 448 | 194 | 1011 | 5.21 | 337.0 |
| 8 | Wyoming | 4 | 593 | 746 | 275 | 1339 | 4.87 | 334.8 |
| 9 | UNLV | 4 | 654 | 1236 | 281 | 1890 | 6.73 | 472.5 |
| 10 | Hawai'i | 5 | 754 | 1365 | 375 | 2119 | 5.65 | 423.8 |
| 11 | Utah State | 4 | 799 | 1045 | 287 | 1844 | 6.43 | 461.0 |
| 12 | Boise State | 4 | 840 | 832 | 294 | 1672 | 5.69 | 418.0 |