2021 Big 12 Conference Leaders Sacks - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Oklahoma State | 13 | 51.0 | 345 | 3.92 |
| 2 | Baylor | 13 | 42.0 | 286 | 3.23 |
| 3 | Iowa State | 12 | 31.0 | 206 | 2.58 |
| 4 | Oklahoma | 12 | 29.0 | 190 | 2.42 |
| 5 | West Virginia | 12 | 25.0 | 170 | 2.08 |
| 5 | Kansas State | 12 | 25.0 | 141 | 2.08 |
| 7 | Texas | 12 | 20.0 | 122 | 1.67 |
| 8 | Texas Tech | 12 | 18.0 | 127 | 1.50 |
| 9 | TCU | 11 | 14.0 | 106 | 1.27 |
| 9 | Kansas | 11 | 14.0 | 94 | 1.27 |