2021 Big 12 Conference Leaders Sacks - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 19.0 | 123 | 4.75 |
| 2 | Oklahoma | 6 | 15.0 | 90 | 2.50 |
| 3 | Iowa State | 5 | 13.0 | 88 | 2.60 |
| 3 | Kansas State | 6 | 13.0 | 68 | 2.17 |
| 5 | West Virginia | 4 | 11.0 | 77 | 2.75 |
| 6 | Baylor | 5 | 10.0 | 76 | 2.00 |
| 7 | Texas | 4 | 8.0 | 50 | 2.00 |
| 8 | TCU | 4 | 7.0 | 59 | 1.75 |
| 8 | Kansas | 4 | 7.0 | 45 | 1.75 |
| 10 | Texas Tech | 5 | 5.0 | 38 | 1.00 |