2021 Big 12 Conference Leaders Tackles For Loss Allowed - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Kansas | 10 | 49.0 | 143 | 4.90 |
| 2 | Oklahoma State | 10 | 53.0 | 163 | 5.30 |
| 3 | Iowa State | 11 | 56.0 | 223 | 5.09 |
| 4 | Texas | 10 | 57.0 | 208 | 5.70 |
| 5 | Texas Tech | 10 | 60.0 | 212 | 6.00 |
| 6 | Oklahoma | 11 | 65.0 | 265 | 5.91 |
| 7 | TCU | 10 | 66.0 | 280 | 6.60 |
| 8 | Kansas State | 11 | 67.0 | 273 | 6.09 |
| 9 | Baylor | 11 | 74.0 | 263 | 6.73 |
| 10 | West Virginia | 12 | 76.0 | 369 | 6.33 |