2021 Big 12 Conference Leaders Total Defense - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | West Virginia | 1 | 35 | 60 | 52 | 95 | 1.83 | 95.0 |
| 2 | Oklahoma | 1 | 55 | 123 | 63 | 178 | 2.83 | 178.0 |
| 3 | TCU | 1 | 61 | 76 | 41 | 137 | 3.34 | 137.0 |
| 4 | Oklahoma State | 1 | 102 | 234 | 83 | 336 | 4.05 | 336.0 |
| 5 | Kansas State | 1 | 100 | 176 | 68 | 276 | 4.06 | 276.0 |
| 6 | Kansas | 1 | 165 | 98 | 63 | 263 | 4.17 | 263.0 |
| 7 | Texas Tech | 1 | 31 | 343 | 88 | 374 | 4.25 | 374.0 |
| 8 | Baylor | 1 | 161 | 120 | 62 | 281 | 4.53 | 281.0 |
| 9 | Iowa State | 1 | 45 | 230 | 60 | 275 | 4.58 | 275.0 |