2021 Big 12 Conference Leaders Total Defense - Games Won Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 12 | 1098 | 2456 | 783 | 3554 | 4.54 | 296.2 |
| 2 | Iowa State | 7 | 739 | 1201 | 417 | 1940 | 4.65 | 277.1 |
| 3 | Texas Tech | 7 | 545 | 1812 | 482 | 2357 | 4.89 | 336.7 |
| 4 | Baylor | 12 | 1339 | 2542 | 782 | 3881 | 4.96 | 323.4 |
| 5 | Kansas State | 8 | 825 | 1600 | 487 | 2425 | 4.98 | 303.1 |
| 6 | West Virginia | 6 | 819 | 1113 | 363 | 1932 | 5.32 | 322.0 |
| 7 | Oklahoma | 11 | 1240 | 3072 | 753 | 4312 | 5.73 | 392.0 |
| 8 | Texas | 5 | 745 | 1049 | 310 | 1794 | 5.79 | 358.8 |
| 9 | Kansas | 2 | 329 | 508 | 144 | 837 | 5.81 | 418.5 |
| 10 | TCU | 5 | 711 | 1198 | 290 | 1909 | 6.58 | 381.8 |