2021 Big 12 Conference Leaders Opponent First Downs - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 13 | 60 | 114 | 23 | 197 | 15.2 |
| 2 | Iowa State | 12 | 91 | 99 | 13 | 203 | 16.9 |
| 3 | Kansas State | 12 | 86 | 115 | 15 | 216 | 18.0 |
| 3 | West Virginia | 12 | 94 | 111 | 11 | 216 | 18.0 |
| 5 | Baylor | 13 | 90 | 134 | 29 | 253 | 19.5 |
| 6 | Texas Tech | 12 | 96 | 143 | 16 | 255 | 21.3 |
| 7 | Texas | 12 | 117 | 127 | 17 | 261 | 21.8 |
| 8 | Oklahoma | 12 | 98 | 146 | 19 | 263 | 21.9 |
| 9 | TCU | 11 | 122 | 114 | 20 | 256 | 23.3 |
| 10 | Kansas | 11 | 145 | 116 | 12 | 273 | 24.8 |