2021 Big 12 Conference Leaders Opponent First Downs - Games in December/January Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Kansas State | 1 | 9 | 4 | 2 | 15 | 15.0 |
| 2 | West Virginia | 1 | 13 | 4 | 0 | 17 | 17.0 |
| 3 | Iowa State | 1 | 8 | 10 | 2 | 20 | 20.0 |
| 4 | Oklahoma State | 2 | 8 | 31 | 3 | 42 | 21.0 |
| 5 | Texas Tech | 1 | 4 | 17 | 1 | 22 | 22.0 |
| 6 | Baylor | 2 | 20 | 21 | 5 | 46 | 23.0 |
| 7 | Oklahoma | 1 | 13 | 12 | 1 | 26 | 26.0 |