2021 Big 12 Conference Leaders Opponent Penalties - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Texas Tech | 7 | 44 | 390 | 6.3 | 55.7 |
| 1 | Kansas State | 6 | 38 | 325 | 6.3 | 54.2 |
| 3 | Oklahoma | 6 | 37 | 300 | 6.2 | 50.0 |
| 3 | Oklahoma State | 9 | 56 | 439 | 6.2 | 48.8 |
| 5 | Iowa State | 7 | 39 | 389 | 5.6 | 55.6 |
| 6 | Kansas | 7 | 34 | 270 | 4.9 | 38.6 |
| 7 | Baylor | 8 | 38 | 330 | 4.8 | 41.3 |
| 8 | West Virginia | 8 | 33 | 280 | 4.1 | 35.0 |
| 8 | Texas | 8 | 33 | 273 | 4.1 | 34.1 |
| 10 | TCU | 7 | 24 | 216 | 3.4 | 30.9 |