2021 Big 12 Conference Leaders Rushing Defense - In The 4th Quarter through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 13 | 104 | 296 | 2.85 | 4 | 26 | 18 | 8 | 2 |
| 2 | Oklahoma State | 14 | 111 | 258 | 2.32 | 4 | 56 | 13 | 9 | 2 |
| 3 | Kansas State | 13 | 119 | 432 | 3.63 | 1 | 43 | 28 | 14 | 7 |
| 4 | Baylor | 14 | 136 | 402 | 2.96 | 5 | 34 | 26 | 16 | 4 |
| 4 | Oklahoma | 13 | 101 | 411 | 4.07 | 5 | 75 | 24 | 16 | 3 |
| 6 | Texas Tech | 13 | 123 | 509 | 4.14 | 3 | 45 | 32 | 17 | 4 |
| 7 | West Virginia | 13 | 158 | 609 | 3.85 | 4 | 53 | 41 | 18 | 5 |
| 8 | Texas | 12 | 131 | 665 | 5.08 | 8 | 33 | 37 | 19 | 10 |
| 9 | Kansas | 12 | 137 | 743 | 5.42 | 11 | 45 | 36 | 22 | 6 |
| 10 | TCU | 12 | 140 | 887 | 6.34 | 10 | 80 | 43 | 28 | 7 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||