2021 Big 12 Conference Leaders Rushing Defense - From Opponent's 1 To 20 Yard Line through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | West Virginia | 11 | 38 | 92 | 2.42 | 0 | 9 | 2 | 0 | 0 |
| 2 | Texas Tech | 12 | 40 | 153 | 3.83 | 0 | 25 | 6 | 4 | 1 |
| 2 | Texas | 12 | 41 | 163 | 3.98 | 0 | 17 | 7 | 4 | 0 |
| 4 | Iowa State | 12 | 45 | 111 | 2.47 | 0 | 21 | 4 | 5 | 2 |
| 4 | Baylor | 10 | 46 | 188 | 4.09 | 0 | 42 | 5 | 5 | 2 |
| 6 | Oklahoma | 12 | 41 | 159 | 3.88 | 0 | 75 | 6 | 6 | 1 |
| 6 | TCU | 11 | 43 | 298 | 6.93 | 1 | 80 | 8 | 6 | 3 |
| 8 | Kansas State | 12 | 45 | 163 | 3.62 | 0 | 28 | 4 | 7 | 1 |
| 8 | Kansas | 10 | 36 | 317 | 8.81 | 1 | 80 | 9 | 7 | 3 |
| 10 | Oklahoma State | 14 | 77 | 382 | 4.96 | 0 | 56 | 10 | 11 | 4 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||