2021 Big 12 Conference Leaders Long Receiving Plays - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Xavier Worthy | Texas | FR | WR | 5 | 15 | 9 | 6 | 3 | 2 | 2 | 1 | 0 | 0 |
| 2 | Quentin Johnston | TCU | SO | WR | 3 | 12 | 8 | 4 | 2 | 2 | 1 | 1 | 0 | 0 |
| 2 | Tyquan Thornton | Baylor | SR | WR | 5 | 11 | 3 | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| 4 | Taye Barber | TCU | SR | WR | 3 | 8 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 4 | Derius Davis | TCU | SR | WR | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 4 | Dominic DiNunzio | TCU | SO | TE | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 4 | Drew Estrada | Baylor | SR | WR | 5 | 4 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| 4 | Erik Ezukanma | Texas Tech | JR | WR | 4 | 13 | 5 | 4 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Keenan Garber | Kansas St | SO | WR | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Jeremiah Hall | Oklahoma | SR | TE | 3 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Jadon Haselwood | Oklahoma | SO | WR | 2 | 2 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Xavier Hutchinson | Iowa State | SR | WR | 5 | 8 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Sam James | WVU | JR | WR | 3 | 4 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Malik Knowles | Kansas St | JR | WR | 3 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 4 | Travis Koontz | Texas Tech | SR | TE | 3 | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 4 | Kendre Miller | TCU | SO | RB | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Marvin Mims | Oklahoma | SO | WR | 3 | 2 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Joshua Moore | Texas | JR | WR | 5 | 8 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 4 | Brennan Presley | Okla St | SO | WR | 4 | 9 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 4 | Deuce Vaughn | Kansas St | SO | RB | 3 | 7 | 3 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Marcus Washington | Texas | JR | WR | 5 | 4 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 4 | Jordan Whittington | Texas | SO | WR | 3 | 9 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 4 | Darren Wilson Jr. | Iowa State | SR | WR | 5 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |