2021 Big 12 Conference Leaders Passing - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Caleb Williams | Oklahoma | FR | QB | 6 | 133 | 82 | 61.7 | 1143 | 8.6 | 13 | 3 | 161.58 | 22.2 | 190.5 |
| 2 | Casey Thompson | Texas | JR | QB | 8 | 164 | 104 | 63.4 | 1420 | 8.7 | 15 | 5 | 160.24 | 20.5 | 177.5 |
| 3 | Donovan Smith | Texas Tech | FR | QB | 6 | 135 | 82 | 60.7 | 1118 | 8.3 | 7 | 2 | 144.45 | 22.5 | 186.3 |
| 4 | Brock Purdy | Iowa State | SR | QB | 7 | 240 | 169 | 70.4 | 1757 | 7.3 | 9 | 8 | 137.63 | 34.3 | 251.0 |
| 5 | Spencer Sanders | Okla St | JR | QB | 9 | 285 | 174 | 61.1 | 2079 | 7.3 | 14 | 10 | 131.52 | 31.7 | 231.0 |
| 6 | Jarret Doege | WVU | SR | QB | 8 | 277 | 179 | 64.6 | 1879 | 6.8 | 8 | 10 | 123.91 | 34.6 | 234.9 |
| 7 | Gerry Bohanon | Baylor | JR | QB | 6 | 127 | 73 | 57.5 | 790 | 6.2 | 6 | 3 | 120.60 | 21.2 | 131.7 |
| 8 | Jason Bean | Kansas | JR | QB | 7 | 124 | 66 | 53.2 | 766 | 6.2 | 2 | 4 | 103.99 | 17.7 | 109.4 |
Note: To qualify, player must have played in 75% of his team's games and have a minimum of 15.0 pass attempts per game played.