2021 Conference USA Leaders Scoring Defense - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | UAB | 8 | 22 | 2 | 21 | 0 | 0 | 159 | 19.9 |
| 2 | Charlotte | 6 | 30 | 4 | 28 | 0 | 0 | 220 | 36.7 |
| 3 | Rice | 6 | 31 | 5 | 31 | 0 | 1 | 234 | 39.0 |
| 4 | Marshall | 7 | 22 | 6 | 20 | 0 | 0 | 170 | 24.3 |
| 4 | North Texas | 7 | 23 | 6 | 23 | 0 | 0 | 179 | 25.6 |
| 4 | Western Kentucky | 8 | 34 | 6 | 32 | 0 | 0 | 254 | 31.8 |
| 7 | Florida Atlantic | 6 | 23 | 7 | 21 | 2 | 2 | 188 | 31.3 |
| 7 | Louisiana Tech | 6 | 25 | 7 | 25 | 0 | 1 | 198 | 33.0 |
| 9 | Southern Mississippi | 6 | 25 | 8 | 25 | 0 | 0 | 199 | 33.2 |
| 9 | Florida International | 6 | 35 | 8 | 32 | 0 | 1 | 268 | 44.7 |
| 11 | Middle Tennessee | 8 | 31 | 9 | 30 | 1 | 1 | 247 | 30.9 |
| 11 | UTSA | 7 | 29 | 9 | 25 | 0 | 0 | 226 | 32.3 |
| 13 | UTEP | 7 | 23 | 10 | 21 | 0 | 1 | 191 | 27.3 |
| 13 | Old Dominion | 7 | 25 | 10 | 24 | 1 | 0 | 206 | 29.4 |