2021 Conference USA Leaders Scoring Defense - All Games through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | UAB | 13 | 41 | 6 | 36 | 1 | 0 | 302 | 23.2 |
| 2 | Charlotte | 12 | 55 | 8 | 52 | 1 | 0 | 408 | 34.0 |
| 3 | Florida Atlantic | 12 | 39 | 10 | 35 | 3 | 2 | 309 | 25.8 |
| 4 | Rice | 12 | 57 | 11 | 55 | 0 | 2 | 434 | 36.2 |
| 5 | Middle Tennessee | 13 | 42 | 12 | 40 | 2 | 1 | 334 | 25.7 |
| 5 | North Texas | 13 | 46 | 12 | 45 | 0 | 0 | 357 | 27.5 |
| 5 | Louisiana Tech | 12 | 53 | 12 | 50 | 1 | 1 | 408 | 34.0 |
| 8 | Marshall | 13 | 39 | 13 | 36 | 0 | 0 | 309 | 23.8 |
| 8 | Southern Mississippi | 12 | 42 | 13 | 42 | 0 | 1 | 335 | 27.9 |
| 10 | UTSA | 14 | 44 | 14 | 37 | 1 | 0 | 345 | 24.6 |
| 10 | Western Kentucky | 14 | 53 | 14 | 51 | 0 | 0 | 411 | 29.4 |
| 12 | Florida International | 12 | 62 | 15 | 57 | 0 | 1 | 476 | 39.7 |
| 13 | UTEP | 13 | 40 | 16 | 38 | 0 | 1 | 328 | 25.2 |
| 14 | Old Dominion | 13 | 44 | 18 | 41 | 1 | 0 | 361 | 27.8 |