2021 Conference USA Leaders Passing Defense - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Marshall | 7 | 212 | 118 | 55.7 | 1295 | 6.1 | 9 | 7 | 114.38 | 30.3 | 185.0 |
| 2 | UAB | 8 | 255 | 142 | 55.7 | 1648 | 6.5 | 15 | 6 | 124.68 | 31.9 | 206.0 |
| 2 | Middle Tennessee State | 8 | 315 | 185 | 58.7 | 2055 | 6.5 | 18 | 9 | 126.68 | 39.4 | 256.9 |
| 4 | North Texas | 7 | 218 | 135 | 61.9 | 1490 | 6.8 | 13 | 3 | 136.27 | 31.1 | 212.9 |
| 5 | UTEP | 7 | 210 | 115 | 54.8 | 1454 | 6.9 | 9 | 2 | 125.16 | 30.0 | 207.7 |
| 6 | Old Dominion | 7 | 243 | 156 | 64.2 | 1846 | 7.6 | 17 | 4 | 147.81 | 34.7 | 263.7 |
| 7 | Florida Atlantic | 6 | 191 | 125 | 65.4 | 1467 | 7.7 | 11 | 6 | 142.69 | 31.8 | 244.5 |
| 7 | Louisiana Tech | 6 | 192 | 131 | 68.2 | 1481 | 7.7 | 9 | 5 | 143.29 | 32.0 | 246.8 |
| 9 | Western Kentucky | 8 | 271 | 168 | 62.0 | 2182 | 8.1 | 12 | 9 | 137.60 | 33.9 | 272.8 |
| 10 | UTSA | 7 | 249 | 148 | 59.4 | 2153 | 8.6 | 17 | 3 | 152.19 | 35.6 | 307.6 |
| 11 | Rice | 6 | 162 | 105 | 64.8 | 1440 | 8.9 | 11 | 4 | 156.96 | 27.0 | 240.0 |
| 12 | Southern Miss | 6 | 148 | 99 | 66.9 | 1341 | 9.1 | 12 | 6 | 161.65 | 24.7 | 223.5 |
| 13 | FIU | 6 | 181 | 134 | 74.0 | 1697 | 9.4 | 15 | 2 | 177.93 | 30.2 | 282.8 |
| 14 | Charlotte | 6 | 159 | 106 | 66.7 | 1728 | 10.9 | 16 | 7 | 182.36 | 26.5 | 288.0 |